I'd do a 40R on a built motor with a dog box and dss axles all around...fuel system is the fun part.
I'm working on a dual fuel rail set up right now for my own build. It's going hand in hand with a new manifold. I'm also doing triple 255's in tank.
running my primary injectors on a reasonable street sized injector and factory fpr and a single 255...then two of the 255's feed a turbosmart fpr and runs my big injectors...they all collect to one return line to the tank.
Should have no issues with street driving as it is mearly factory fuel system for driving around town...pending where you have your secondary injectors to come on.