The only reason I can see a stock location 'large' turbo spooling quicker than a rotated set up is simply because of the small exhaust housing. But a rotated turbo has a better powerband and more peak torque for the same reason. The smaller exhaust housing on the stock location turbo will also greatly affect power once boost is turned up on race fuel.
I've priced stock location big turbo kits and rotated kits and when using a turbo such as a Blouch Dominator series the price difference is literally a couple hunderd bucks. So unless you just have gripes about a rotated kit or already have every bolt-on and supporting modification needed for a large stock locatoin turbo I dont see why you wouldnt go rotated.