Yes, they might not fit. 215's will fit, but sometimes have rubbing issues on a 17x7.5 wheel if the car is really lowered.
To fit 225's on a 17x7.5 et48 wheel, you'll need to roll the fenders most likely. If the car is lowered, you'll definitely have issues.
I just put 215/45/17 Yoko ES100's on some Rota Tarmacs(17x7.5 et48). Mine fit without rubbing, but are a close call. I'm going to have to be careful about suspension choices, now.