Originally Posted by DeleriousZ
Match the rolling diameter of the tires and it will be fine (see 225/40 and 255/35.)
I have read that it is acceptable if the difference in rolling diameter is less than 1/4" BUT and here is the reason that people say no to a staggered setup. It will cause your wheel bearings to wear prematurely and you will run the possibility of eating up your center differential. For a "cool look" replacing a wheel bearing is going to cost you $70 a pop and a center diff is going to cost you a little over a $1000 if you do the work. All things to consider.